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Two p53 suppressors MDM2 and MDMX,which are highly expressed in tumors, often work together as one complex to inactivate p53 bymediating its ubiquitination and degradation as well as to directly inhibit p53 transcriptionalactivity in a feedback fashion.
Effect modification occurs when theassociation between two or more factors varies by one ormore additional factors.
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Amatching group of patients who have not receivedthe drug is identified and followed up to serveas control. This is only partly an academic exercise; it will ultimatelyalso be a very personal task
This is only partly an academic exercise; it will ultimatelyalso be a very personal task. In Brunner& Suddarth’s Textbook of Medical-Surgical Nursing (11th ed.) Philadelphia, PA:Lippincott Williams & Wilkins, p
In Brunner& Suddarth’s Textbook of Medical-Surgical Nursing (11th ed.) Philadelphia, PA:Lippincott Williams & Wilkins, p. Dermis is well supplied with lymph andblood capillaries
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